What Is a Fetal Stem CellWritten by anand12
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The fetal stem cells are found in developing fetus bone marrow and other tissues like liver and kidney. The fetal blood is also a reservoir of hematopoietic stem cells, which has more proliferation power than the cord blood or adult bone marrow hematopoietic stem cells. The fetal blood in the first trimester also contains non hematopoietic mesenchymal cells which helps in haemopoiesis and also can differentiate into other different types of cells. The fetal stem cells, both hematopoietic as well as mesenchymal has greater advantage over their adult stem cells counterpart. They have a better intrinsic homing and engraftment, multipotency and lower immunogenicity. The implementation of fetal stem cells arise lesser ethical issues than that of the embryonic stem cells and they have more potential to differentiate when compared to their adult counterpart. Fetal stem cell have great potential in the field of medicine with it being a great promise as therapeutic tool in the ex vivo gene therapy and cell transplantation procedures.
The fetal stem cells are pluripotent in nature and can grow into any of the cell types. These stem cells can germinate indefinitely up to the life of the organism. The stem cells differentiate to form two types of cells that can either be a differentiated cell like blood, skin etc. or it may develop into another pleuripotent stem cell. Pluripotent fetal stem cells have been cultivated in vitro to produce pluripotent stem cell lines. The ethical question connected to the research of fetal stem cell is that the opponents say the fetuses also have human rights and by doing a research using them which results in their killing is depriving them of these rights. However, the proponents of fetal stem research say that the benefits associated with the fetal stem cell research far outweighs the ethical issues regarding the use of fetuses.
Uses Of Fetal Stem Cells:
Millions of persons suffer with maladies that are curable by utilizing stem cells for therapeutic purposes. While the development and use of such therapies may take time because of the different factors including ethical issues, neurons from aborted fetuses have already been used for grafting into the brains of patients suffering with Parkinson’s disease. The most important work in this connection was undertaken during 1990-2000, by Anders Bjorklund and his colleagues at Lund University in Sweden. It was shown that the neuron grafted from aborted fetuses, when transplanted, dramatically relieved the patient from slow movements and rigidity. However, several other neurological disorders involving precise network of connections in sensory motors, visual system are difficult to be dealt with cell therapy.